I work around sick people a lot so I'm always coming into contact with a variety of bacteria, viruses, molds, etc. Every time I feel that my body is working against something new (i.e., scratchy, sore throat, general malaise, increased fatigue, fever), I pop two of these capsules before bed with plenty of water. I get my 7-8.5 hrs of sleep and the next morning I experience a noticeable improvement in my symptoms. I even tested my own hypothesis by not taking the mushrooms when I was feeling a scratchy throat, and sure enough, my symptoms had worsened the next day by evidence of fever and swollen lymph glands in my throat. I then took two capsules with the swollen glands, and another two that same night. The next morning, my glands were no longer swollen, my fever was gone, and my throat was no longer sore. I believe in the power of these mushrooms and I believe in Paul Stamets and his team to deliver a quality product backed by claims made. I am a life-long customer and I encourage those around me to give them a try.